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    GenerationPharmacy
    Dermatology

    Different Types of Hair Loss and Treatment Solutions

    An overview of the common types of hair loss and the ingredients prescribers may use, including in compounded formulas.

    G
    Generation Pharmacy
    April 23, 2025

    Understanding Hair Loss: Beyond Simple Balding

    Hair loss affects millions of people regardless of gender, though the patterns and underlying causes often differ significantly. A dermatologist identifies the type of hair loss, which guides treatment.

    Major Types of Hair Loss

    Androgenetic Alopecia (Pattern Hair Loss)

    The most common form of hair loss, affecting both men and women:

    • In men: Typically begins with recession at the temples and/or thinning at the crown
    • In women: Usually presents as diffuse thinning across the top of the scalp with preservation of the frontal hairline

    Key mechanism: Sensitivity to dihydrotestosterone (DHT), which causes miniaturization of hair follicles over time, leading to progressively thinner and shorter hairs until follicles eventually become dormant.

    Telogen Effluvium

    A temporary form of diffuse hair shedding triggered by:

    • Major physical stress (surgery, illness, childbirth)
    • Significant weight loss
    • Nutritional deficiencies
    • Certain medications
    • Hormonal fluctuations

    Key mechanism: A larger percentage of hairs than normal enter the telogen (resting) phase of the hair cycle simultaneously, resulting in increased shedding 2-3 months after the triggering event.

    Alopecia Areata

    An autoimmune condition characterized by:

    • Well-defined circular patches of complete hair loss
    • Unpredictable pattern of remission and recurrence
    • In severe cases, can progress to total scalp hair loss (alopecia totalis) or complete body hair loss (alopecia universalis)

    Key mechanism: The immune system attacks hair follicles, causing inflammation and disruption of hair growth.

    Traction Alopecia

    Hair loss resulting from physical stress on hair follicles, often due to:

    • Tight hairstyles (ponytails, braids, buns)
    • Hair extensions or weaves
    • Frequent use of hair tools that pull on the hair

    Key mechanism: Constant tension damages follicles and can eventually lead to permanent hair loss if the pulling force continues over years.

    Scarring (Cicatricial) Alopecia

    A group of disorders that destroy hair follicles and replace them with scar tissue, including:

    • Lichen planopilaris
    • Frontal fibrosing alopecia
    • Discoid lupus erythematosus
    • Folliculitis decalvans

    Key mechanism: Inflammation damages the stem cell reservoir of the follicle, resulting in permanent destruction and inability to regrow hair.

    Ingredients Prescribers Use

    These are ingredients a prescriber may order. Your prescriber chooses the ingredients and strengths. Compounded medications are not FDA-approved.

    For Androgenetic Alopecia

    Topical Ingredients

    A prescriber may combine:

    • Minoxidil: At the strength the prescriber writes
    • Finasteride: A 5α-reductase inhibitor, used topically off-label
    • Dutasteride: Another 5α-reductase inhibitor, used off-label for hair loss
    • Corticosteroids: Such as fluocinolone, when the prescriber adds one
    • Other ingredients: Such as caffeine or melatonin, when the prescriber adds them

    Oral Options

    A prescriber may also order an oral medication:

    • Finasteride: At the strength the prescriber writes
    • Dutasteride: Off-label for hair loss
    • Spironolactone: Used off-label by some prescribers for female pattern hair loss

    For Telogen Effluvium

    Care usually starts with finding and addressing the trigger, such as illness, a medication, or low iron. Your prescriber decides whether any treatment is needed.

    For Alopecia Areata

    A dermatologist may prescribe:

    • Topical or injected corticosteroids
    • Minoxidil
    • Topical immunomodulators, such as tacrolimus
    • JAK inhibitors, including FDA-approved oral products for severe alopecia areata

    See a Dermatologist Early

    If you notice unusual hair loss, see a dermatologist. Some types, such as scarring alopecia, cause permanent damage, so an early diagnosis matters.

    Working With Your Prescriber

    Your prescriber may also check hormones, iron and other labs, and review your scalp care. Response to any hair loss treatment varies and takes time to judge, so keep your follow-up visits. If your prescriber writes a compounded formula, they can send it to us and we will prepare it as written.

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    Disclaimer: This content is provided for informational purposes only and is not intended as medical advice, diagnosis, or treatment. Always consult with a qualified healthcare professional regarding any medical condition or before starting any new treatment.

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