For Providers · Prescribing Guide
Writing a compounded prescription.
Everything you need to write a clean compounded prescription: strength conventions, click-based sigs, standardized supplies, and ePrescribing. Questions? A pharmacist answers the phone.
The Essentials
Anatomy of a compounded prescription
Five elements make a compounded Rx unambiguous. Include all five and a clean Rx moves straight through pharmacist review into the compounding queue — no clarification callback needed.
Drug + strength
Estradiol 0.5 mg/mL topical cream
Name the active(s) and concentration. For combinations, list each component (e.g., Bi-Est 80/20 2.5 mg/mL).
Base / dosage form
Topical cream in Topi-CLICK
Specify the form — cream, gel, capsule, troche, suppository — and the dispenser if metered dosing matters.
Sig with clicks or units
Apply 2 clicks (0.5 mL = 0.25 mg) topically once daily
Include both the click count and the mg equivalent so the patient and pharmacist stay aligned.
Quantity + days supply
Qty: 15 mL · Days Supply: 30
Write volume (mL) or count (capsules/troches) plus a standard 30, 60, or 90-day supply.
Refills
Refills: 2
Compounded BHRT is typically refilled after follow-up labs — most providers write 2 refills with a 3-month recheck.
Metered Topical Dosing
The Topi-CLICK system: clicks, concentrations, supplies
Topi-CLICK applicators meter by volume — we compound the concentration to your patient's dose, so the sig stays constant and titration only changes the strength. Choose the dispenser by desired days supply.
30-Day Supply
Topi-CLICK 35
2 clicks (0.5 mL) daily
15 mL fill — 0.25 mL/click
Standard monthly fill. Concentration = prescribed daily dose ÷ 0.5 mL.
60-Day Supply
Topi-CLICK 35
2 clicks (0.5 mL) daily
30 mL fill — 0.25 mL/click
Same dispenser and concentration as the 30-day, larger fill volume.
90-Day Supply
Topi-CLICK 140
2 clicks (1 mL) daily
90 mL fill — 0.5 mL/click
Larger dispenser, half the cream concentration — same daily dose in 1 mL.
Sample Rx: "Estradiol 0.5 mg/mL topical cream in Topi-CLICK. Sig: Apply 2 clicks (0.5 mL = 0.25 mg) topically once daily. Qty: 15 mL. Days Supply: 30. Refills: 2." The same 2-click sig works at every strength — only the cream concentration changes.
What We Compound
Available dosage forms
Topical creams & gels
BHRT, dermatology, pain, hair — transdermal delivery in Topi-CLICK or pump dispensers
Oral capsules
Custom strengths, combination actives, allergen-free fillers
Sublingual troches & ODTs
Rapid absorption bypassing first-pass metabolism
Topical solutions, serums & foams
Scalp and dermatology applications in dropper or pump bottles
Vaginal creams & suppositories
Local hormone therapy with minimal systemic absorption
Nasal sprays & lacquers
Specialty routes for select actives
We are a 503A non-sterile compounding pharmacy operating under USP 795 and USP 800. We do not compound sterile preparations, injectables, or IV medications.
Clinical quick references
Estradiol Shortage — Conversion Guide
Patch → compounded dose equivalencies with Topi-CLICK click counts
Complete Formulary
Public formulary by category; sign in for strengths
Ingredient Library
Pharmacy-grade ingredients with mechanism and formulation data
Join the Provider Network
Formulary updates and a direct pharmacist line
Ready to send your first Rx?
ePrescribe through SiPrescribe (NCPDP: 5685271) or call our pharmacist line for formulation questions.