How Topi-CLICK Dispensers Work: Clicks, mL, and Why Your Dose Stays Consistent
Your hormone cream comes in a Topi-CLICK for a reason: it meters exact volumes, 0.25 mL per click on the 35, 0.5 mL on the 140, so your dose is identical every day. Here's how the math works.
The short answer: a Topi-CLICK is a metered-dose dispenser that delivers an exact volume of cream with every click. The Topi-CLICK 35 gives 0.25 mL per click. The larger Topi-CLICK 140 gives 0.5 mL per click. It meters volume, not milligrams: the hormone concentration inside is compounded specifically for you, so the same two-clicks-a-day routine can deliver any dose your prescriber chooses. When your dose changes, the concentration changes and your clicks stay the same. Which is exactly why prescribers and pharmacies like it.
KeyPoints
- Topi-CLICK 35 = 0.25 mL per click; Topi-CLICK 140 = 0.5 mL per click, always volume, never mg
- Concentration is personalized per patient, so milligrams per click differ between prescriptions
- Dose changes happen by changing cream strength, not your click count
- 30/60/90-day supplies are straightforward volume math from your daily clicks
- Used at our pharmacy for BHRT creams like estradiol, Bi-Est, and progesterone
EndKeyPoints
Why not just use a jar and a fingertip?
Because "a pea-sized amount" is not a dose. Hormone therapy lives and dies on consistency, absorption through skin already varies with site and skin condition, so the applied amount is the one variable that should never wobble. A jar invites scooping variability; a syringe is precise but clumsy. The Topi-CLICK solves it mechanically: twist the base until it clicks, and a fixed volume of cream is pushed onto the applicator pad. Every click, every day, identical.
The two models, by the numbers
| Dispenser | Volume per Click | Total Capacity | Typical Use |
|---|---|---|---|
| Topi-CLICK 35 | 0.25 mL | 35 mL | 30–60 day fills at lower daily volumes |
| Topi-CLICK 140 | 0.5 mL | 140 mL | 90-day fills and higher daily volumes |
Note what's missing from that table: milligrams. The dispenser has no idea what's in the cream. It dispenses volume. That's not a limitation; it's the design insight the whole system is built on.
Volume is metered, milligrams are compounded
Here's the division of labor. The dispenser guarantees the mL; the pharmacy sets the mg by compounding your cream at a concentration made for you. Say your prescriber wants 0.5 mg of estradiol daily and a one-mL-per-day routine. We compound a 0.5 mg/mL cream. You apply 4 clicks from a Topi-CLICK 35, which is 4 × 0.25 mL = 1 mL. If your follow-up labs lead your prescriber to raise the dose to 0.75 mg, we compound 0.75 mg/mL. And your routine remains exactly 4 clicks. The patient-facing instruction never changes; titration happens invisibly in the concentration. Fewer instruction changes means fewer dosing mistakes, which is the practical payoff.
How 30, 60, and 90-day supplies are calculated
| Daily Routine | Daily Volume | Supply | Fill |
|---|---|---|---|
| 4 clicks, Topi-CLICK 35 | 1 mL | 30 days | 30 mL |
| 2 clicks, Topi-CLICK 35 (double-strength cream) | 0.5 mL | 60 days | 30 mL |
| 2 clicks, Topi-CLICK 140 | 1 mL | 90 days | 90 mL |
That last row is the popular one. It is the same 1 mL daily volume and the same concentration as the 30-day option. It is simply dispensed as 2 larger clicks from the bigger dispenser and filled for 90 days. Your prescriber writes the days-supply; we do the volume math and choose the dispenser accordingly. You can see this system applied to real conversions in our estradiol patch shortage guide, where every cream strength uses the same 4-click sig.
Practical tips for daily use
- Prime a new dispenser per the included instructions before your first dose, priming clicks fill the mechanism and don't count as doses
- Rotate application sites (inner forearm, inner thigh, behind the knee) as your prescriber directs, and apply to clean, dry skin
- Wash hands after applying, and avoid skin-to-skin transfer to partners, children, and pets until the area is dry
- Don't double up after a missed dose unless your prescriber says to, consistency beats correction
Questions about your dispenser?
If anything about your clicks, strength, or days supply seems off, call us before improvising, a pharmacist will walk through the math with you at 424-228-1049. New to compounded hormones? Start with the BHRT patient guide, browse the formulation catalog, or send your provider our prescribing guide.
Frequently Asked Questions
How much cream is one Topi-CLICK click?
It depends on the dispenser model: the Topi-CLICK 35 delivers 0.25 mL per click, and the larger Topi-CLICK 140 delivers 0.5 mL per click. The dispenser meters volume mechanically, so every click is the same amount of cream regardless of how hard you twist.
How many milligrams of hormone is one click?
There is no universal answer. And that's by design. The dispenser meters volume (mL); the milligrams in that volume depend on the concentration your pharmacy compounded, which is personalized to your prescription. Two patients can both apply two clicks daily and receive completely different doses.
Why do my clicks stay the same when my dose changes?
Because the pharmacy changes the concentration of the cream, not your routine. If your prescriber doubles your dose, we compound the cream at double strength and you keep applying the same clicks. Consistent routine, fewer dosing errors.
How do 30, 60, and 90-day supplies work with Topi-CLICK?
Supply length is simple volume math: daily mL (clicks × mL per click) times days equals total mL dispensed. For example, 1 mL daily for 30 days is a 30 mL fill in a Topi-CLICK 35; the same regimen for 90 days uses a 90 mL fill in a Topi-CLICK 140 at 2 clicks (0.5 mL each) daily.
Do I need to prime a new Topi-CLICK?
Yes, a new dispenser needs priming clicks before the first dose to fill the internal mechanism (follow the printed instructions that come with your fill, typically several clicks until cream appears). Priming clicks don't count toward your dose, and we account for priming volume when we fill it.
Disclaimer: This content is provided for informational purposes only and is not intended as medical advice, diagnosis, or treatment. Always consult with a qualified healthcare professional regarding any medical condition or before starting any new treatment.
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