TRPV1 agonist
Capsaicin
Pale orange to red cream
Typical Strength
0.025%–0.1%
Formulations
0 compounds
Formula
C₁₈H₂₇NO₃
Mol. Weight
305.41 g/mol
How It Works
Mechanism of action
TRPV1 agonist that initially excites then desensitizes pain fibers, depleting substance P from sensory neurons. With repeated use it reduces neuropathic and arthritic pain signaling at the source.
Did you know?
Capsaicin is what makes chili peppers hot — the same molecule that triggers a burn ultimately quiets pain nerves when used consistently.
What compounding can change
When Capsaicin is compounded for one patient, your prescriber can choose the concentration, combine it with other ingredients, and pick the base. Commercial products come in fixed strengths and bases.
Safety Considerations
Please note: Compounded medications require a prescription from a licensed prescriber for an individual patient. Compounded medications are not FDA-approved. The FDA does not review them for safety, effectiveness or quality. A compounded medication is not the same as, or a generic version of, any FDA-approved drug. This page is general information, not medical advice. Your prescriber decides whether a treatment is right for you and sets the final ingredients, strength and dosage form.