Antifungal
Ketoconazole
White to off-white cream or shampoo base
Typical Strength
1%–2%
Formulations
0 compounds
Formula
C₂₆H₂₈Cl₂N₄O₄
Mol. Weight
531.43 g/mol
How It Works
Mechanism of action
Imidazole antifungal that blocks ergosterol synthesis in fungal cell membranes via CYP450 14α-demethylase inhibition. Also has mild anti-androgen and anti-inflammatory effects useful in seborrheic dermatitis.
What compounding can change
When Ketoconazole is compounded for one patient, your prescriber can choose the concentration, combine it with other ingredients, and pick the base. Commercial products come in fixed strengths and bases.
Safety Considerations
Please note: Compounded medications require a prescription from a licensed prescriber for an individual patient. Compounded medications are not FDA-approved. The FDA does not review them for safety, effectiveness or quality. A compounded medication is not the same as, or a generic version of, any FDA-approved drug. This page is general information, not medical advice. Your prescriber decides whether a treatment is right for you and sets the final ingredients, strength and dosage form.