Calcium channel blocker (topical)
Nifedipine
Yellow ointment or cream
Typical Strength
0.2%–0.5%
Formulations
0 compounds
Formula
C₁₇H₁₈N₂O₆
Mol. Weight
346.33 g/mol
How It Works
Mechanism of action
Calcium channel blocker that relaxes vascular and sphincter smooth muscle. Topically, it relaxes the anal sphincter and improves blood flow to heal chronic anal fissures — avoiding the systemic effects of oral dosing.
What compounding can change
When Nifedipine is compounded for one patient, your prescriber can choose the concentration, combine it with other ingredients, and pick the base. Commercial products come in fixed strengths and bases.
Safety Considerations
Please note: Compounded medications require a prescription from a licensed prescriber for an individual patient. Compounded medications are not FDA-approved. The FDA does not review them for safety, effectiveness or quality. A compounded medication is not the same as, or a generic version of, any FDA-approved drug. This page is general information, not medical advice. Your prescriber decides whether a treatment is right for you and sets the final ingredients, strength and dosage form.