Antibiotic
Clindamycin
Clear to slightly yellow gel
Typical Strength
1%
Formulations
2 compounds
Formula
C₁₈H₃₃ClN₂O₅S
Mol. Weight
424.98 g/mol
How It Works
Mechanism of action
Binds the 50S ribosomal subunit to inhibit bacterial protein synthesis. Effective against Cutibacterium acnes. Also suppresses complement-derived chemotaxis, reducing inflammatory lesion counts.
What compounding can change
When Clindamycin is compounded for one patient, your prescriber can choose the concentration, combine it with other ingredients, and pick the base. Commercial products come in fixed strengths and bases.
Safety Considerations
Available In
Formulations with Clindamycin
Benzoyl Peroxide / Clindamycin / Tretinoin / Niacinamide Gel
Acne combination with a customizable, clinician-directed intensity.
Tretinoin / Clindamycin / Azelaic Acid / Niacinamide Cream
The retinoid-antibiotic-azelaic acne combination without benzoyl peroxide, for patients who cannot tolerate bleaching or dryness.
Commonly paired with
These ingredients frequently appear alongside Clindamycin in our formulations.
Please note: Compounded medications require a prescription from a licensed prescriber for an individual patient. Compounded medications are not FDA-approved. The FDA does not review them for safety, effectiveness or quality. A compounded medication is not the same as, or a generic version of, any FDA-approved drug. This page is general information, not medical advice. Your prescriber decides whether a treatment is right for you and sets the final ingredients, strength and dosage form.