PDE5 inhibitor
Tadalafil
White to pale yellow troche
Typical Strength
2.5–20 mg/unit
Formulations
6 compounds
Formula
C₂₂H₁₉N₃O₄
Mol. Weight
389.40 g/mol
How It Works
Mechanism of action
Long-acting PDE5 inhibitor with a 17.5-hour half-life — enabling daily low-dose dosing. Also inhibits PDE11, which may contribute to effects on smooth muscle beyond the corpora cavernosa.
Did you know?
Tadalafil has a half-life of about 17.5 hours, longer than other PDE5 inhibitors.
What compounding can change
When Tadalafil is compounded for one patient, your prescriber can choose the concentration, combine it with other ingredients, and pick the base. Commercial products come in fixed strengths and bases.
Safety Considerations
Available In
Formulations with Tadalafil
Tadalafil Dissolvable or Capsule
Flexible tadalafil programs (daily or PRN) in patient-preferred forms.
Sildenafil / Tadalafil / Apomorphine Dissolvable
Three ED mechanisms in one dissolvable troche, strengths set by the prescriber.
Sildenafil / Tadalafil Dissolvable
Dual-PDE5 troche pairing on-demand and longer-window coverage in one unit (clinician-screened).
Vardenafil / Tadalafil Dissolvable
Vardenafil with tadalafil in one dissolvable dose, compounded to the prescriber's order.
Tadalafil / Oxytocin Dissolvable
Clinician-led intimacy protocol with high-touch counseling.
Sildenafil / Tadalafil / Apomorphine / Oxytocin Dissolvable
Four-mechanism sublingual for prescribers who combine vascular, dopaminergic and oxytocin support.
Commonly paired with
These ingredients frequently appear alongside Tadalafil in our formulations.
Please note: Compounded medications require a prescription from a licensed prescriber for an individual patient. Compounded medications are not FDA-approved. The FDA does not review them for safety, effectiveness or quality. A compounded medication is not the same as, or a generic version of, any FDA-approved drug. This page is general information, not medical advice. Your prescriber decides whether a treatment is right for you and sets the final ingredients, strength and dosage form.